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The connection is direct, well-documented, and mechanistically clear
A 2025 Bayesian network meta-analysis reported that 10.6% of patients experienced diarrhea while using semaglutide, according to Comparative gastrointestinal adverse effects of GLP-1 receptor agonists and multi-target analogs in type 2 diabetes
This treatment works by targeting hunger signals and metabolic regulation, creating a reliable pathway for consistent weight loss
However, combining it with insulin or sulfonylureas requires careful medical supervision to prevent severe low blood sugar
They also slow down how quickly food leaves your stomach (called gastric emptying)
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